Protein phosphatase 1G Antibody / PPM1G (RQ8033)

Description

Protein phosphatase 1G, also known as PPM1G, is a member of the PP2C family of serine/threonine phosphatases that play a key role in the regulation of cellular stress response pathways and cell cycle progression. It is particularly involved in the dephosphorylation of pre-mRNA splicing factors and other regulatory proteins, thereby influencing gene expression, RNA splicing, and cell signaling cascades.

PPM1G has multiple isoforms generated by alternative splicing. These isoforms exhibit distinct subcellular localization and may differ in their enzymatic activity or interaction with specific substrates, making them important targets for studies involving post-transcriptional regulation and signal transduction. Dysregulation of Protein phosphatase 1G has been implicated in various disease processes, including cancer and neurodegenerative conditions.

A high-quality Protein phosphatase 1G antibody is essential for researchers aiming to investigate the role of this phosphatase in cellular processes and disease models. The Protein phosphatase 1G antibody enables specific detection of endogenous protein isoforms in tissues and cultured cells. It can be applied in western blot, immunohistochemistry, and immunofluorescence assays. NSJ Bioreagents offers a Protein phosphatase 1G antibody validated for high specificity and consistent performance across multiple applications, helping researchers achieve reproducible and accurate results.

Application Notes

Optimal dilution of the Protein phosphatase 1G antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids E48-Q457) was used as the immunogen for the Protein phosphatase 1G antibody.

Storage

After reconstitution, the Protein phosphatase 1G antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.