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Home >> Antibodies >> Oncoprotein 18 Antibody / OP18 / Stathmin 1

Oncoprotein 18 Antibody / OP18 / Stathmin 1 [clone STMN1/8439] (V5506)

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  Catalog No Formulation Size Price (USD)  
Image V5506-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5506-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5506SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human colon carcinoma tissue with Oncoprotein 18 antibody (clone STMN1/8439). Inset: PBS used in place of primary Ab (secondary Ab negative control).
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IHC staining of FFPE human colon carcinoma tissue with Oncoprotein 18 antibody (clone STMN1/8439). Inset: PBS used in place of primary Ab (secondary Ab negative control).
SDS-PAGE analysis of purified, BSA-free Oncoprotein 18 antibody (clone STMN1/8439) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name STMN1/8439
Purity Protein A/G affinity
UniProt P16949
Localization Cytoplasm, Cytoskeleton
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Oncoprotein 18 antibody is available for research use only.
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Description

Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Application Notes

Optimal dilution of the Oncoprotein 18 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Oncoprotein 18 antibody.

Storage

Aliquot the Oncoprotein 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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