• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> MAEL Antibody / Maelstrom homolog

MAEL Antibody / Maelstrom homolog (RQ8389)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image RQ8389 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
Bulk quote request
Flow cytometry testing of fixed and permeabilized human U-251 cells with MAEL antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MAEL antibody.
›
Flow cytometry testing of fixed and permeabilized human U-251 cells with MAEL antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MAEL antibody.
Western blot testing of human 1) K562 and 2) U-251 cell lysate with MAEL antibody. Predicted molecular weight ~49 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q96JY0
Applications Western Blot : 0.5-1ug/ml
Flow Cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This MAEL antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Description

The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Application Notes

Optimal dilution of the MAEL antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (E73-Q347) was used as the immunogen for the MAEL antibody.

Storage

After reconstitution, the MAEL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all MAEL antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.