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Home >> Antibodies >> Galectin 13 Antibody / LGALS13 / GAL13

Galectin 13 Antibody / LGALS13 / GAL13 [clone PP13/8897] (V5623)

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  Catalog No Formulation Size Price (USD)  
Image V5623-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5623-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5623SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human placental tissue with Galectin-13 antibody (clone PP13/8897). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human placental tissue with Galectin-13 antibody (clone PP13/8897). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Galectin-13 antibody (clone PP13/8897) as confirmation of purity and integrity of antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name PP13/8897
Purity Protein A/G affinity
UniProt Q9UHV8
Localization Cytoplasm, Cell membrane
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Galectin 13 antibody is available for research use only.
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Description

It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Application Notes

Optimal dilution of the Galectin 13 antibody should be determined by the researcher.

Immunogen

A recombinant human Galectin-13 protein fragment (amino acids 1-139) was used as the immunogen for the Galectin 13 antibody.

Storage

Aliquot the Galectin 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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