FOXL2 Antibody (RQ6867)

Description

FOXL2 (Forkhead box protein L2) is a transcription factor belonging to the forkhead/winged-helix family, characterized by a conserved DNA-binding domain that regulates gene expression during development and tissue maintenance. FOXL2 is predominantly expressed in ovarian granulosa cells and certain ocular tissues, where it plays key roles in cell differentiation, growth regulation, and long-term tissue homeostasis.

Functionally, FOXL2 is involved in pathways that influence folliculogenesis, hormone signaling, and extracellular matrix remodeling. It also participates in broader transcriptional networks that coordinate cell identity and developmental timing. Due to its specific expression profile, FOXL2 serves as an important marker in developmental biology and reproductive research.

The FOXL2 antibody enables precise detection of endogenous FOXL2 in applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the FOXL2 antibody from NSJ Bioreagents to measure protein levels, determine subcellular localization, and study transcription factor activity under defined experimental conditions. With high specificity and consistent performance, the FOXL2 antibody supports detailed investigations into transcriptional regulation, reproductive biology, and developmental gene networks.

Application Notes

Optimal dilution of the FOXL2 antibody should be determined by the researcher.

Immunogen

Amino acids ACARQPELAMMHCSYWDHD from the human protein were used as the immunogen for the FOXL2 antibody.

Storage

After reconstitution, the FOXL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.