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Home >> Antibodies >> Fibrinogen alpha Antibody / FGA

Fibrinogen alpha Antibody / FGA (F55117)

  Catalog No Formulation Size Price (USD)  
Image F55117-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F55117-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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Western blot testing of human blood plasma lysate with Fibrinogen alpha antibody. Predicted molecular weight ~70 kDa (alpha isoform), ~95 kDa (alpha-E isoform).
Immunofluorescent staining of fixed and permeabilized human HepG2 cells with Fibrinogen alpha antibody (green) and DAPI nuclear stain (blue).
IHC staining of FFPE human breast carcinoma tissue with Fibrinogen alpha antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
UniProt P02671
Applications Western Blot : 1:500-1:1000
Immunohistochemistry (FFPE) : 1:10-1:50
Immunofluorescence : 1:10-1:50
Limitations This Fibrinogen alpha antibody is available for research use only.
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Description

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Fibrinogen alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 116-144 from the human protein was used as the immunogen for this Fibrinogen alpha antibody.

Storage

Store at 4oC for up to one month. For long term, aliquot the Fibrinogen alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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