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Home >> Antibodies >> DCAMKL1 Antibody / Doublecortin-like and CAM kinase-like 1 / DCLK1

DCAMKL1 Antibody / Doublecortin-like and CAM kinase-like 1 / DCLK1 (F55057)

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  Catalog No Formulation Size Price (USD)  
Image F55057-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F55057-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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Western blot testing of 1) human brain, 2) mouse brain, 3) rat brain and 4) TT cell lysate with DCAMKL1 antibody. Predicted molecular weight: ~82 kDa and ~47 kDa (multiple isoforms).
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Western blot testing of 1) human brain, 2) mouse brain, 3) rat brain and 4) TT cell lysate with DCAMKL1 antibody. Predicted molecular weight: ~82 kDa and ~47 kDa (multiple isoforms).
Western blot testing of 1) human brain and 2) mouse brain tissue lysate with DCAMKL1 antibody. Predicted molecular weight: ~82 kDa and ~47 kDa (multiple isoforms).
Western blot testing of 1) human brain and 2) mouse brain tissue lysate with DCAMKL1 antibody. Predicted molecular weight: ~82 kDa and ~47 kDa (multiple isoforms).
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9JLM8
Applications Western Blot : 1:1000-1:5000
Limitations This DCAMKL1 antibody is available for research use only.
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Description

This gene encodes a member of the protein kinase superfamily and the doublecortin family called Doublecortin-like and CAM kinase-like 1 (DCAMKL1) or Doublecortin-like kinase 1 (DCLK1). The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.

Application Notes

Titration of the DCAMKL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 690-720 from the human protein was used as the immunogen for this DCAMKL1 antibody.

Storage

Aliquot the DCAMKL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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