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Home >> Antibodies >> Zebrafish Ptp4a2 Antibody / Protein tyrosine phosphatase type IVA 2

Zebrafish Ptp4a2 Antibody / Protein tyrosine phosphatase type IVA 2 (RZ1072)

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Image RZ1072 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 539
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Western blot analysis of Ptp4a2 protein using Zebrafish Ptp4a2 antibody and zebrafish embryo tissue lysate. The predicted molecular weight of Ptp4a2 is ~19 kDa.
Western blot analysis of Ptp4a2 protein using Zebrafish Ptp4a2 antibody and zebrafish embryo tissue lysate. The predicted molecular weight of Ptp4a2 is ~19 kDa.
Availability 2-3 weeks
Species Reactivity Zebrafish
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q5U3R3
Applications Western Blot : 0.5-1 ug/ml
Limitations This Zebrafish Ptp4a2 antibody is available for research use only.
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Description

Protein tyrosine phosphatase type IVA 2 is an enzyme that in humans is encoded by the PTP4A2 gene. The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Application Notes

Optimal dilution of the Zebrafish Ptp4a2 antibody should be determined by the researcher.

Immunogen

An E.coli-derived zebrafish Ptp4a2 recombinant protein (amino acids M7-D75) was used as the immunogen for the Zebrafish Ptp4a2 antibody.

Storage

After reconstitution, the Zebrafish Ptp4a2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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