Zebrafish Myca Antibody / Myc-A / c-Myc-A (RZ1241)

Description

Transcriptional regulator Myc A is a key member of the myelocytomatosis transcription factor family and plays a central role in controlling gene expression related to cell growth, proliferation, differentiation, and metabolism. In zebrafish, Myc A is an essential regulator during embryogenesis and is involved in the development of multiple organ systems.

Myc A functions by forming heterodimers with other transcriptional regulators and binding to specific DNA sequences to activate or repress target genes. It promotes the expression of genes involved in cell cycle progression, protein synthesis, and energy metabolism, while also modulating genes associated with apoptosis and cellular stress responses. This makes Myc A critical for balancing growth signals with environmental and developmental cues.

During zebrafish development, Myc A is expressed in proliferative regions such as the brain, somites, and hematopoietic tissues. Its expression is tightly regulated to ensure proper tissue formation and to prevent excessive or disorganized cell growth. Dysregulation of Myc A can lead to developmental abnormalities and has been linked to tumor formation in zebrafish models, making it a valuable tool in cancer biology research.

Because of its strong conservation across vertebrates and its fundamental role in transcriptional control, zebrafish Myc A is widely used in studies of developmental genetics, stem cell function, oncogenesis, and metabolic regulation.

Application Notes

Optimal dilution of the Zebrafish Myca antibody should be determined by the researcher.

Immunogen

E. coli-derived zebrafish Myca recombinant protein (amino acids K21-H419) was used as the immunogen for the Zebrafish Myca antibody.

Storage

After reconstitution, the Zebrafish Myca antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.