Zebrafish Insulin like growth factor 1 Antibody / Igf1 (RZ1230)

Description

Insulin like growth factor 1, also known as IGF1, is a peptide growth factor that plays a key role in regulating cell growth, differentiation, and survival. In zebrafish, insulin like growth factor 1 is essential for normal embryonic development, tissue regeneration, and metabolic regulation.

IGF1 is produced mainly in the liver and acts both locally and systemically through endocrine and paracrine signaling. It mediates many of the growth promoting effects of growth hormone and functions by binding to its specific receptor on the cell surface, triggering downstream signaling pathways that influence cell cycle progression, protein synthesis, and apoptosis inhibition.

In zebrafish, insulin like growth factor 1 is involved in the development of multiple organs including the brain, heart, and skeletal muscle. It also supports fin regeneration and contributes to recovery from injury by promoting cell proliferation and tissue remodeling. IGF1 expression is sensitive to nutritional status and environmental factors, making it a key biomarker for growth and metabolic studies.

Due to its strong conservation across vertebrates and its broad physiological importance, zebrafish insulin like growth factor 1 is widely used in research related to developmental biology, growth regulation, endocrine function, metabolic disease, and regenerative medicine.

Application Notes

Optimal dilution of the Zebrafish Insulin like growth factor 1 antibody should be determined by the researcher.

Immunogen

E. coli-derived zebrafish Insulin like growth factor 1 recombinant protein (amino acids G45-M161) was used as the immunogen for the Zebrafish Insulin like growth factor 1 antibody.

Storage

After reconstitution, the Zebrafish Insulin like growth factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.