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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.
Store the Uroplakin 3A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
UP3a, UPIIIA, UPK3A, UroplakinIII (UPIII), Uroplakin3A, Uroplakin 3A antibody
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