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Home >> Antibodies >> Uroplakin 3A Antibody

Uroplakin 3A Antibody (V2295)

  Catalog No Formulation Size Price (USD)  
Image V2295-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 539
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V2295-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 249
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V2295SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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Western blot analysis of human HEK293 lysate using Uroplakin 3A antibody.
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Protein A affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 7380
Localization Cell surface
Applications Western Blot : 0.5-1ug/ml
Limitations This Uroplakin 3A antibody is available for research use only.
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Description

Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Immunogen

A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Storage

Store the Uroplakin 3A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Alternate Names

UP3a, UPIIIA, UPK3A, UroplakinIII (UPIII), Uroplakin3A, Uroplakin 3A antibody

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