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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TRIP10 Antibody / CIP4 [clone 28T70] (RQ8543)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ8543 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ug | 439 |
|
| Availability | 1-3 days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 28T70 |
| Purity | Affinity chromatography |
| UniProt | Q15642 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This TRIP10 antibody is available for research use only. |
|
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Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. [UniProt]
Optimal dilution of the TRIP10 antibody should be determined by the researcher.
A synthetic peptide from human Cdc42-interacting protein 4 / Thyroid receptor-interacting protein 10 protein was used as the immunogen for the TRIP10 antibody.
Store the TRIP10 antibody at -20oC.
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