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Home >> Antibodies >> SLITRK1 Antibody / SLIT and NTRK-like protein 1

SLITRK1 Antibody / SLIT and NTRK-like protein 1 (RQ8780)

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  Catalog No Formulation Size Price (USD)  
Image RQ8780 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Flow cytometry testing of fixed human U-251 cells with SLITRK1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= SLITRK1 antibody.
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Flow cytometry testing of fixed human U-251 cells with SLITRK1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= SLITRK1 antibody.
Western blot testing of human 1) U-87 MG, 2) U-251 and 3) U-2 OS cell lysate with SLITRK1 antibody. Predicted molecular weight ~78 kDa, observed here at ~55 kDa.
Availability 1-3 days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q96PX8
Applications Western Blot : 1-2ug/ml
Flow Cytometry : 1-3ug/million cells
ELISA : 0.1-0.5ug/ml
Limitations This SLITRK1 antibody is available for research use only.
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Description

SLITRK1 (SLIT and NTRK-like family, member 1) is a human gene that codes for a transmembrane and signalling protein that is part of the SLITRK gene family, which is responsible for synapse regulation and presynaptic differentiation in the brain. This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the SLITRK1 antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (amino acids D22-D696) was used as the immunogen for the SLITRK1 antibody.

Storage

After reconstitution, the SLITRK1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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