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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
RSK2 Antibody / RPS6KA3 / Ribosomal protein S6 kinase alpha 3 [clone 28R24] (RQ8298)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ8298 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 439 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 28R24 |
| Purity | Affinity chromatography |
| UniProt | P51812 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This RSK2 antibody is available for research use only. |
|
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|
Ribosomal protein S6 kinase alpha 3 (RPS6KA3, RSK2) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. [UniProt]
Optimal dilution of the RSK2 antibody should be determined by the researcher.
A synthetic peptide derived from human RSK2 / RPS6KA3 was used as the immunogen for the RSK2 antibody.
Store the RSK2 antibody at -20oC.
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