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Home >> Antibodies >> Recombinant Uroplakin 1B Antibody / UPK1B

Recombinant Uroplakin 1B Antibody / UPK1B [clone UPK1B/9258R] (V5386)

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  Catalog No Formulation Size Price (USD)  
Image V5386-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5386-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5386SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Microvalidated Recrabbitmono
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IHC staining of FFPE human bladder carcinoma tissue with recombinant Uroplakin 1B antibody (clone UPK1B/9258R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human bladder carcinoma tissue with recombinant Uroplakin 1B antibody (clone UPK1B/9258R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human bladder carcinoma tissue with recombinant Uroplakin 1B antibody (clone UPK1B/9258R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name UPK1B/9258R
Purity Protein A/G affinity
UniProt O75841
Localization Membrane
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant Uroplakin 1B antibody is available for research use only.
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Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

Application Notes

Optimal dilution of the recombinant Uroplakin 1B antibody should be determined by the researcher.

Immunogen

A recombinant fragment (within amino acids 109-229) of human Uroplakin 1B/UPK1B protein was used as the immunogen for the recombinant Uroplakin 1B antibody.

Storage

Aliquot the recombinant Uroplakin 1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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