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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the alpha-chain (i.e. in S-100A and S-100B) but not on the beta-chain of S-100 (i.e. in S-100B). This antibody can be used to localize S-100A in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, epithelial and myoepithelial cells of the breast, salivary and sweat glands. Neoplasms derived from these cells also express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Optimal dilution of the recombinant S100A1 antibody should be determined by the researcher.
A recombinant fragment (within amino acids 1-94) of human S100A1 protein was used as the immunogen for the recombinant S100A1 antibody.
Aliquot the recombinant S100A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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