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Home >> Antibodies >> Recombinant CD10 Antibody / Neprilysin / CALLA

Recombinant CD10 Antibody / Neprilysin / CALLA [clone MME/9617R] (V5445)

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  Catalog No Formulation Size Price (USD)  
Image V5445-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5445-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5445SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Microvalidated Recrabbitmono
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IHC staining of FFPE human colon tissue with recombinant CD10 antibody (clone MME/9617R). Inset: PBS used in place of primary Ab (secondary Ab negative control).
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IHC staining of FFPE human colon tissue with recombinant CD10 antibody (clone MME/9617R). Inset: PBS used in place of primary Ab (secondary Ab negative control).
SDS-PAGE analysis of purified, BSA-free recombinant CD10 antibody (clone MME/9617R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name MME/9617R
Purity Protein A/G affinity
UniProt P08473
Localization Cytoplasm, Cell membrane
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant CD10 antibody is available for research use only.
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Description

Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA) and Neprilysin. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitts, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Application Notes

Optimal dilution of the recombinant CD10 antibody should be determined by the researcher.

Immunogen

A recombinant fragment (within amino acids 400-600) of human CD10 protein was used as the immunogen for the recombinant CD10 antibody.

Storage

Aliquot the recombinant CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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