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Home >> Antibodies >> Recombinant Cathepsin D Antibody / CTSD

Recombinant Cathepsin D Antibody / CTSD [clone CTSD/9613R] (V5441)

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  Catalog No Formulation Size Price (USD)  
Image V5441-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5441-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5441SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human pancreas with recombinant Cathepsin D antibody (clone CTSD/9613R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human pancreas with recombinant Cathepsin D antibody (clone CTSD/9613R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Cathepsin D antibody (clone CTSD/9613R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name CTSD/9613R
Purity Protein A/G affinity
UniProt P07339
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant Cathepsin D antibody is available for research use only.
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Description

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52kDa preprocathepsin D that is cleaved and glycosylated to form a 48kDa procathepsin D and then further cleaved to produce 34kDa and 14kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Application Notes

Optimal dilution of the recombinant Cathepsin D antibody should be determined by the researcher.

Immunogen

A His-tagged CTSD protein was used as the immunogen for the recombinant Cathepsin D antibody.

Storage

Aliquot the recombinant Cathepsin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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