PVALB Antibody / Parvalbumin [clone AOFB-16] (RQ8890)

Description

Parvalbumin (PVALB) is a small calcium-binding protein belonging to the EF-hand superfamily. It is highly expressed in fast-twitch muscle fibers and specific populations of neurons, where it contributes to rapid calcium buffering and relaxation processes. In the nervous system, PVALB is a well-established marker for certain GABAergic interneurons.

PVALB plays a role in regulating intracellular calcium signaling, influencing muscle contraction dynamics and neuronal excitability. Altered PVALB expression has been associated with neurological conditions, including epilepsy and neurodevelopmental disorders. It is also widely studied in neuroanatomical mapping and muscle physiology research.

Using a high-quality PVALB antibody enables precise detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A PVALB antibody from NSJ Bioreagents ensures sensitivity and reproducibility for studies involving neuronal identity, calcium signaling, and muscle biology. Selecting the appropriate PVALB antibody is essential for accurate and consistent experimental results.

Application Notes

Optimal dilution of the PVALB antibody should be determined by the researcher.

Immunogen

A peptide sequence specific to Parvalbumin was used as the immunogen for the PVALB antibody.

Storage

After reconstitution, the PVALB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.