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Home >> Antibodies >> Platelet glycoprotein 4 Antibody / CD36

Platelet glycoprotein 4 Antibody / CD36 [clone CD36/7216] (V5825)

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  Catalog No Formulation Size Price (USD)  
Image V5825-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5825-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5825SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human spleen tissue with Platelet glycoprotein 4 antibody (clone CD36/7216). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human spleen tissue with Platelet glycoprotein 4 antibody (clone CD36/7216). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Western blot testing of human heart tissue lysate with Platelet glycoprotein 4 antibody (clone CD36/7216). Expected molecular weight: 53-88 kDa depending on level of glycosylation.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG
Clone Name CD36/7216
Purity Protein A/G affinity
UniProt P16671
Localization Cell membrane, Cytoplasm (Golgi)
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Western Blot : 2-4ug/ml
Limitations This Platelet glycoprotein 4 antibody is available for research use only.
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Description

Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.

Application Notes

Optimal dilution of the Platelet glycoprotein 4 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 200-400 from human Platelet glycoprotein 4 protein was used as the immunogen for the Platelet glycoprotein 4 antibody.

Storage

Aliquot the Platelet glycoprotein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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