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Home >> Antibodies >> Phospho-mTOR Antibody (pS2448)

Phospho-mTOR Antibody (pS2448) [clone IFF-13] (RQ8814)

  Catalog No Formulation Size Price (USD)  
Image RQ8814 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
Microvalidated Recrabbitmono
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IHC staining of FFPE human breast cancer tissue with Phospho-mTOR antibody antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Western blot testing of human HEK293 cell lysate with Phospho-mTOR antibody.
Availability 1-3 days
Species Reactivity Human
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name IFF-13
UniProt P42345
Applications Western Blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This Phospho-mTOR antibody is available for research use only.
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Description

Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins and functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). [UniProt]

Application Notes

Optimal dilution of the Phospho-mTOR antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to the region of human mTOR protein surrounding phosphorylated serine 2448 was used as the immunogen for the Phospho-mTOR antibody (pS2448).

Storage

Store the Phospho-mTOR antibody at -20oC.

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