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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Homeobox protein Nkx-2.1, also called Thyroid transcription factor-1 (TTF-1) is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.
Optimal dilution of the NKX2.1 antibody should be determined by the researcher.
A recombinant fragment (within amino acids 1-200) of human TTF-1 protein was used as the immunogen for the NKX2.1 antibody.
Aliquot the NKX2.1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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