IL7RA Antibody / Interleukin-7 receptor alpha / CD127 [clone 22I71] (RQ8889)

Description

Interleukin-7 receptor alpha (IL7RA) is a type I transmembrane glycoprotein that forms part of the receptor complex for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP). It plays a crucial role in lymphocyte development, survival, and homeostasis, particularly in T-cell and B-cell biology.

Genetic variations in IL7RA have been associated with susceptibility to autoimmune diseases, such as multiple sclerosis and type 1 diabetes, as well as immune deficiency disorders. IL7RA signaling regulates lymphocyte proliferation, differentiation, and maintenance, making it a valuable focus for immunological and therapeutic research.

Using a high-quality IL7RA antibody enables accurate detection of the protein in applications including western blot, immunohistochemistry, and flow cytometry. An IL7RA antibody from NSJ Bioreagents delivers consistent and reproducible performance for studies on immune signaling, lymphocyte biology, and disease pathogenesis. Selecting the right IL7RA antibody ensures reliable results in both basic research and clinical investigations.

Application Notes

Optimal dilution of the IL7RA antibody should be determined by the researcher.

Immunogen

A peptide sequence specific to Interleukin-7 receptor alpha was used as the immunogen for the IL7RA antibody.

Storage

After reconstitution, the IL7RA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.