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Home >> Antibodies >> ICMT Antibody / Protein-S-isoprenylcysteine O-methyltransferase

ICMT Antibody / Protein-S-isoprenylcysteine O-methyltransferase (RQ8661)

  Catalog No Formulation Size Price (USD)  
Image RQ8661 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Western blot testing of 1) rat brain and 2) rat C6 cell lysate with ICMT antibody. Predicted molecular weight ~32 kDa.
Availability 1-3 days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity chromatography
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt O60725
Applications Western Blot : 1-2ug/ml
ELISA : 0.1-0.5ug/ml
Limitations This ICMT antibody is available for research use only.
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Description

Protein-S-isoprenylcysteine O-methyltransferase is an enzyme that in humans is encoded by the ICMT gene. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Application Notes

Optimal dilution of the ICMT antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (amino acids E13-L284) was used as the immunogen for the ICMT antibody.

Storage

After reconstitution, the ICMT Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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