DDX1 Antibody [clone 11E5.] (RQ6287)

Description

DEAD box protein 1 (DDX1) is a multifunctional RNA helicase that plays a critical role in RNA processing and cellular regulation. As part of the DEAD-box family, DDX1 uses ATP hydrolysis to unwind RNA secondary structures, supporting processes such as transcription, splicing, ribosome biogenesis, and RNA transport. A DDX1 antibody is a key reagent for studying these functions in molecular biology.

In addition to RNA metabolism, DDX1 has been implicated in DNA damage repair. It interacts with key repair factors at double-strand breaks, suggesting a bridging role between RNA processing and genome integrity. The use of a DDX1 antibody in experimental models helps researchers trace these interactions and evaluate its contribution to stress responses and chromosomal stability.

DDX1 has growing relevance in biomedical research due to its connections with cancer and viral infection. Overexpression of the protein has been reported in tumors, where it supports proliferation and metabolic reprogramming. It also participates in the replication cycles of certain viruses by binding to viral RNA, positioning DDX1 as an important host factor in virology. A DDX1 antibody allows for detailed assessment of these roles in both health and disease.

NSJ Bioreagents provides a high-quality DDX1 antibody optimized for western blot, immunofluorescence, and immunohistochemistry. By selecting a validated DDX1 antibody, researchers can achieve consistent and sensitive detection to advance studies of RNA regulation, DNA repair, cancer, and viral biology.

Application Notes

Optimal dilution of the DDX1 antibody should be determined by the researcher.

Immunogen

A human recombinant partial protein (amino acids K562-F740) was used as the immunogen for the DDX1 antibody.

Storage

After reconstitution, the DDX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.