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Home >> Antibodies >> c-Fos Antibody / FOS

c-Fos Antibody / FOS [clone IIO-6] (RQ4859)

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  Catalog No Formulation Size Price (USD)  
Image RQ4859 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
Microvalidated Recrabbitmono
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Western blot testing of human 1) HeLa and 2) RT4 cell lysate with c-Fos antibody. Expected molecular weight ~40 kDa, but may be observed at higher molecular weights due to phosphorylation.
Western blot testing of human 1) HeLa and 2) RT4 cell lysate with c-Fos antibody. Expected molecular weight ~40 kDa, but may be observed at higher molecular weights due to phosphorylation.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name IIO-6
Purity Affinity purified
UniProt P01100
Applications Western Blot : 1:500
Limitations This c-Fos antibody is available for research use only.
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Description

c-Fos (FOS) is an immediate early response transcription factor that dimerizes with proteins of the JUN family to form the AP-1 complex. This complex regulates the expression of target genes involved in cell proliferation, differentiation, and survival. A c-Fos antibody is widely used in research to monitor transcriptional activity and cellular responses to stimuli.

c-Fos expression is rapidly induced by growth factors, stress signals, and neuronal activity, making it a key marker of cellular activation. In neuroscience, it is frequently used as an indicator of neuronal activity and plasticity. Employing a c-Fos antibody allows researchers to track changes in gene expression and study signaling pathways in diverse biological contexts.

NSJ Bioreagents provides a high-quality c-Fos antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Selecting the right c-Fos antibody ensures sensitive and reproducible detection in studies of transcriptional regulation, cell signaling, and brain activity.

Application Notes

Optimal dilution of the c-Fos antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human c-Fos / FOS was used as the immunogen for the c-Fos antibody.

Storage

Store the c-Fos antibody at -20oC.

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