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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
BCKDK Antibody / BCKDH kinase [clone 29B01] (RQ8869)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ8869 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 439 |
|
| Availability | 1-2 days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 29B01 |
| Purity | Affinity chromatography |
| UniProt | O14874 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This BCKDK antibody is available for research use only. |
|
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BCKDK functions by phosphorylating and inhibiting the branched-chain alpha-ketoacid dehydrogenase complex, which is responsible for catalyzing the initial step in BCAA catabolism. By regulating the activity of this complex, BCKDK helps maintain a balance of BCAAs in the body, which is essential for various physiological processes. Research has shown that dysregulation of BCKDK activity can lead to metabolic disorders such as maple syrup urine disease and phenylketonuria. Understanding the role of BCKDK in these conditions has paved the way for potential therapeutic interventions targeting this enzyme. Recent studies have also highlighted the potential implications of BCKDK in other health conditions, including cancer and insulin resistance.
Optimal dilution of the BCKDK antibody should be determined by the researcher.
A synthetic peptide specific to human BCKDK protein was used as the immunogen for the BCKDK antibody.
Store the BCKDK antibody at -20oC.
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