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Home >> Antibodies >> BASP1 Antibody / Brain acid soluble protein 1

BASP1 Antibody / Brain acid soluble protein 1 (F55071)

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  Catalog No Formulation Size Price (USD)  
Image F55071-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F55071-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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Western blot testing of human U-251 MG cell lysate with BASP1 antibody. Predicted molecular weight ~23 kDa and ~18 kDa (two isoforms). BASP1 may be observed at higher molecular weights due to SUMOylation. The amount of SDS in SDS-PAGE may also affect the observed size.
Western blot testing of human U-251 MG cell lysate with BASP1 antibody. Predicted molecular weight ~23 kDa and ~18 kDa (two isoforms). BASP1 may be observed at higher molecular weights due to SUMOylation. The amount of SDS in SDS-PAGE may also affect the observed size.
Availability 1-2 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P80723
Applications Western Blot : 1:500-1:1000
Limitations This BASP1 antibody is available for research use only.
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Description

BASP1, or Brain acid soluble protein 1, and also known as NAP22 or CAP-23, is a highly conserved protein found in the brain and nervous system. It plays a pivotal role in regulating neuronal growth, synaptic plasticity, and cell signaling. BASP1 is known to interact with various cellular proteins and lipids, influencing processes such as axonal growth, neurotransmitter release, and neuroprotection. Research has shown that BASP1 is involved in a multitude of cellular processes that are essential for proper brain function. It plays a crucial role in promoting dendritic branching, axonal outgrowth, and neuronal migration during brain development. Additionally, BASP1 is implicated in regulating the release of neurotransmitters such as dopamine and acetylcholine, which are crucial for cognitive functions. Given its pivotal role in brain function, BASP1 dysregulation has been linked to various neurological disorders. Studies have shown that abnormal levels of BASP1 expression are associated with conditions such as Alzheimer's disease, Parkinson's disease, and schizophrenia.

Application Notes

Titration of the BASP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 123-150 from the human protein was used as the immunogen for this BASP1 antibody.

Storage

Aliquot the BASP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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