AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1 [clone AFGH-1] (RQ8894)

Description

Allograft inflammatory factor 1 (AIF-1) is a cytoplasmic, calcium-binding protein predominantly expressed in activated macrophages and microglia. It is involved in the regulation of immune and inflammatory responses, contributing to cell proliferation, migration, and cytokine production. AIF-1 plays roles in vascular pathology, tissue repair, and immune-mediated diseases.

Elevated expression of AIF-1 has been associated with various pathological conditions, including atherosclerosis, autoimmune disorders, and neuroinflammation. It serves as a marker for activated immune cells, making it valuable for studying inflammation-related mechanisms and disease progression.

Using a high-quality AIF-1 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An AIF-1 antibody from NSJ Bioreagents provides reliable performance for research in immunology, neurobiology, and cardiovascular disease. Selecting the right AIF-1 antibody ensures accurate and reproducible experimental outcomes.

Application Notes

Optimal dilution of the AIF-1 antibody should be determined by the researcher.

Immunogen

A peptide sequence specific to Allograft inflammatory factor 1 was used as the immunogen for the AIF-1 antibody.

Storage

After reconstitution, the AIF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.